EFEITOS DO BIOFILME BACTERIANO NA RESISTENCIA A DESINFETANTES HOSPITALARES: REVISÃO DE LITERATURA
DOI:
https://doi.org/10.71328/jht.v8i2.74Palavras-chave:
Biofilmes, Resistência Microbiana a Medicamentos, Controle de Infecções, DesinfetantesResumo
Introdução: As infecções hospitalares são potencializadas pela formação de biofilmes em superfícies e dispositivos médicos, dificultando a eliminação microbiana. A eficácia da desinfecção depende da escolha adequada do agente, sua concentração e o tempo de exposição. Objetivo: Revisar a literatura sobre o impacto do biofilme bacteriano na resistência a desinfetantes hospitalares, abordando formação, mecanismos de resistência e implicações para o controle de infecções. Método: Realizou-se revisão narrativa da literatura recente (2018–2024) em bases como PubMed, SciELO, LILACS e Google Acadêmico, utilizando descritores relacionados a biofilmes, desinfetantes hospitalares e resistência microbiana. Resultados: O controle de biofilmes requer a integração de novas tecnologias, como nanopartículas, enzimas e luz UV-C, capazes de superar a barreira estrutural protetora. Conclusão: O biofilme confere resistência persistente aos desinfetantes, tornando essencial combinar tecnologias inovadoras e rigor na aplicação de protocolos manuais, com treinamento contínuo das equipes para garantir eficácia na prevenção de infecções relacionadas à assistência à saúde.
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